Vitamin E and hepatotoxic agents

Vitamin E and hepatotoxic agents

I . It has been suggested that carbon tetrachloride damages rat liver by accelerating processes of lipid peroxidation at subcellular sites and that the protective action of vitamin E is due to its functioning as an antioxidant in vivo. Direct evidence for these mechanisms in vivo has been sought and is critically examined. 2. The increased production of malondialdehyde by rat liver microsomal f...

Hepatotoxic Effects of Lipid-altering Agents

Dyslipidemia is a major risk factor for coronary heart disease (CHD), and current guidelines support low-density lipoprotein cholesterol (LDL-C) as a primary target of therapy.[1] Previous studies suggest that increasing high-density lipoprotein cholesterol (HDL-C) and reducing triglycerides and small LDL particles may also have a positive impact in prevention.[2] These factors are considered s...

Hepatotoxic agents; mechanism of action and dietary interrelationship.

04 Vitamin E 1999 e

Vitamin E-blended UHMWPE with a Gradient Vitamin E Concentration

INTRODUCTION: Vitamin E-stabilized, radiation cross-linked ultra-high molecular weight polyethylene (UHMWPE) is used in total joint arthroplasty as a bearing surface with low wear and improved mechanical properties compared to irradiated and melted UHMWPE [1]. Vitamin E stabilizes the residual free radicals trapped in the material after irradiation and ensures oxidative resistance, thus resulti...